All hazards › Medications › Glipizide (Glucotrol) & cats

Is Glipizide (Glucotrol) Safe for Cats?

☠️ Toxic
✅ Cross-checked against veterinary poison-control guidance · Oct 2026 audit
⚠️ Educational info only. If your pet just ate or touched something and looks unwell, skip the reading and call your vet — or Pet Poison Helpline (US): (855) 764-7661, ASPCA Poison Control (US): (888) 426-4435.
No. Glipizide can cause profound, life-threatening hypoglycemia in cats — any ingestion requires immediate veterinary contact.

Why it’s a problem

Glipizide forces insulin release, and a cat given a human tablet can crash into severe hypoglycemia with weakness, tremors, and seizures. Cats are tiny, so even one tablet is a large overdose. Prolonged low blood sugar has been reported to cause lasting harm or death without treatment.

How to keep your pet safe

Store glipizide and other diabetes drugs behind closed doors, and clean up dropped pills immediately. Feline diabetes is managed by veterinarians with species-appropriate treatment — never human pills.

Warning signs to watch for

Extreme lethargy, weakness, wobbliness, trembling, drooling, vomiting; severe hypoglycemia: seizures, collapse, unresponsiveness.

When to call the vet

Call your veterinarian or a pet poison hotline immediately — this is not a wait-and-see exposure for a cat. Have the tablet strength and your cat’s weight ready when you call.

Common questions

My cat ate one of my glipizide tablets — what now?

Call your vet or a pet poison hotline right away — one tablet can cause severe low blood sugar in a cat. Do not wait for symptoms to develop.

Wasn’t glipizide once used for diabetic cats?

It has been used under veterinary supervision in specific cases, but dosing is exact and monitored. Human tablets at home doses are dangerous — never self-dose a cat.

More medications hazards for cats

This page is general educational information, not a substitute for professional veterinary advice. Every pet is different — if your animal ate or touched something concerning, contact your veterinarian or a pet poison hotline right away. In the US: Pet Poison Helpline (855) 764-7661, ASPCA Animal Poison Control (888) 426-4435 (fees may apply).